Flagship protocol
Exosomes in. Measured outcomes out.
Signal Exosome Therapy, rolled out clinic by clinic
One flagship protocol. Signal MSC-derived exosome infusions delivered inside vetted partner clinics, with the same panel measured before and after every course. Every patient closes the loop, and every closed loop trains the Signal AI Clock.
The closed loop
Full panel plus Signal Visual Analyzer at the partner clinic. Bloods, methylation, HRV, VO2. This sets the pace-of-aging baseline the protocol is judged against.
Paired reads · week 0 vs week 12
Illustrative cohort mean, n = 24
hs-CRP
-54.2%2.4 → 1.1 mg/L
IL-6
-41.9%3.1 → 1.8 pg/mL
HRV (rMSSD)
+36.6%41 → 56 ms
VO2 max
+10.5%38 → 42 ml/kg/min
Epigenetic gap
-52.9%3.4 → 1.6 yr
Pace of aging
-13.0%1.08 → 0.94 x
Clinic rollout
Miami, FL
Signal Flagship Site
Tokyo
Partner longevity clinic
West Palm Beach, FL
Partner internal medicine
Osaka
Partner clinic
Signal Clinic operates only through vetted partner clinics in jurisdictions where the protocol is legally permitted. Exosome therapy is investigational; all data shown is illustrative sample data.